Essential Foods To HEAL YOUR BODY
Skip to minute-51:35
How do immune checkpoint inhibitors work against cancer?
Immune checkpoints are a normal part of the immune system. Their role is to prevent an immune response from being so strong that it destroys healthy cells in the body.
Immune checkpoints engage when proteins on the surface of immune cells called T cells recognize and bind to partner proteins on other cells, such as some tumor cells. These proteins are called immune checkpoint proteins. When the checkpoint and partner proteins bind together, they send an “off” signal to the T cells. This can prevent the immune system from destroying cancer.
Immunotherapy drugs called immune checkpoint inhibitors work by blocking checkpoint proteins from binding with their partner proteins. This prevents the “off” signal from being sent, allowing the T cells to kill cancer cells.
One such drug acts against a checkpoint protein called CTLA-4. Other immune checkpoint inhibitors act against a checkpoint protein called PD-1 or its partner protein PD-L1. Some tumors turn down the T cell response by producing lots of PD-L1.
Which cancers are treated with immune checkpoint inhibitors?
Immune checkpoint inhibitors are approved to treat some patients with a variety of cancer types, including:
Head and neck cancer
Renal cell cancer (a type of kidney cancer)
Any solid tumor that is not able to repair errors in its DNA that occur when the DNA is copied
In preparation to take Checkpoint Inhibitors
akkermansia muciniphila bacteria, Take a stool test to check the levels of this bacteria… It is extremely important that these bacteria have a high count before taking the Checkpoint inhibitors.
You can't take it as a (pre or probiotic).
It thrives on polyphenols so you must consume (pomegranate / cranberries / green tea) to build up the bacteria count in your system before taking the Checkpoint therapy.
Use “Checkpoint inhibitors” for cancer therapy, and use high dose intravenous vitamin-C